TRPC6 Antibody_华拓生物

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TRPC6 Antibody

产品名称 ： TRPC6 Antibody

中文名称 ：瞬时受体电位离子通道蛋白6抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0402395

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide corresponding to a sequence in the middle region of human TRPC6.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	TRPC6(Transient receptor potential cation channel, subfamily C, member 6), also known as TRP6, is a transient receptor potentialion channel.TRPC6 is a novel member of the TRPC family. The predicted 931-amino acid protein shares 93% identity with mouse Trpc6. Northern blot analysis revealed that TRPC6 is expressed primarily in placenta, lung, spleen, ovary, and small intestine. The TRPC6 gene is mapped on 11q22.1. TRPC6 is a nonselective cation channel that is activated by diacylglycerol(DAG) in a membrane-delimited fashion, independently of protein kinase C. Although TRPC3, the closest structural relative of TRPC6, is activated in the same manner, human TRPC1 and mouse Trpc4 and Trpc5 were unresponsive to DAG. Immunofluorescence studies showed that most TRPC6 expression is confined to podocytes. TRPC6 was also expressed in glomerular endothelial cells.
适用物种：	Hu, Mo, Rat
应用说明：	WB: 1:200-1:1000 IHC: 1:500-1:1000
别　　名：	Short transient receptor potential channel 6;TrpC6;Transient receptor protein 6;TRP-6;TRPC6;TRP6.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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