NOL3 Antibody_华拓生物

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NOL3 Antibody

产品名称 ： NOL3 Antibody

中文名称 ：核仁蛋白3抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0402435

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide corresponding to a sequence in the middle region of human Apoptosis repressor with CARD.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	NOL3(Nucleolar protein 3), also known as ARC, NOP30, CARD2 and MYP, is a protein that in humans is encoded by the NOL3 gene. NOL3 has been shown to interact with SFRS9 and Caspase 8. By genomic sequence analysis, Stoss et al.(1999) determined that the NOL3 gene, which encodes NOP30 and MYP and which they called NOP, is composed of 4 exons. The alternative 5-prime splice site that generates the 2 isoforms is located in exon 2. It is reported that expression of the ARC cDNA encoding the smaller transcript inhibited apoptosis in a dose-dependent manner when coexpressed with CASP8 but not when coexpressed with CASP9. ARC also inhibited apoptosis induced by stimulation of CD95/FAS, tumor necrosis factor receptor-1, and TRAMP/death receptor-3. Enzymatic analysis showed that ARC inhibits the enzymatic activity of CASP8.
适用物种：	Hu, Mo, Rat
应用说明：	WB: 1:200-1:1000
别　　名：	Nucleolar protein 3 ;Apoptosis repressor with CARD ;Muscle-enriched cytoplasmic protein ;Myp ;Nucleolar protein of 30 kDa ;Nop30 ;NOL3 ;ARC , NOP.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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