DLL1 Antibody_华拓生物

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DLL1 Antibody

产品名称 ： DLL1 Antibody

中文名称 ： Notch信号通路Delta样配体1抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0402550

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide corresponding to a sequence at the N-terminus of human DLL1.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	DLL1(DELTA-LIKE 1) also known as DL1 or DELTA1, is a protein that in humans is encoded by the DLL1 gene. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Using FISH, Gray et al.(1999) mapped the DLL1 gene to chromosome 6q27, near a locus for type I diabetes. Functional analysis by Han et al.(2000) suggested that a soluble fusion protein containing the DSL domain of DLL1 and its adjacent 50 N-terminal amino acids increased the viability of hemopoietic cells but inhibited cell death. Jaleco et al.(2001) used a cell coculture assay to show that DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. In contrast, JAG1 did not disturb either B-cell or T-cell/NK-cell development.
适用物种：	Hu, Mo, Rat
应用说明：	WB: 1:200-1:1000
别　　名：	Delta-like protein 1;Drosophila Delta homolog 1;Delta1;H-Delta-1;DLL1;UNQ146/PRO172.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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