| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1/k |
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免 疫 原 ： |
Purified human PAPP-A |
|
产品描述 ： |
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21). This antibody is specific for native human PAPP-A. Heat and SDS-denatured PAPP-A is also recognized, but not acid treated PAPP-A . |
| 适用物种 ： |
H |
|
应用范围 ： |
E |
| 应用说明 ： |
In sandwich ELISA, Product Cat. No. 250257 is used as the capture antibody and biotinylated Product Cat. No. 250220 as detection antibody. Product Cat. No. 250220 only detects unreduced PAPP-A in Western Blotting. Product Cat. No. 250220 gives the strongest signal in IHC compared to Product Cat. No. 250219 and Product Cat. No. 250257. E: 1:8,000; WB: 1:1,000; IHC: 1:200 |
| 别 名 ： |
Pregnancy-associated plasma protein A; Pappalysin-1(precursor); Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 protease; IGFBP-4ase |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/papp-1-24-antibody |
| 标 记 物 ： |
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产品说明 ： |
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