| 克隆类型 : |
Mouse Monoclonal Antibody |
|
亚 型 : |
Mouse IgG1 |
|
免 疫 原 : |
Synthetic human alpha-CGRP adsorbed onto aluminum hydroxide gel |
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产品描述 : |
Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds an epitope within the aa 19-37 of human alpha-CGRP. Based on inhibition ELISA, this antibody cross-reacts up to 12% with human beta-CGRP and human amylin, whereas there is weak cross-reaction (<4%) with rat alpha-CGRP. |
| 适用物种 : |
H, R |
|
应用范围 : |
E, IHC |
| 应用说明 : |
Product Cat. No. 250237 binds free human alpha-CGRP in solution. The ELISA dilution guideline applies to human alpha-CGRP coated directly at 1.0 ug/ml. Product Cat. No. 250237 (as biotinylated detection antibody) forms a sandwich ELISA pair with Product Cat. No. 250238 (as capture antibody) for measuring human alpha-CGRP, giving a detection limit of 0.13 nmol/l in an unoptimized buffer assay. The antibody is used in IHC with paraffin-embedded tissues. E: 1:8,000; IHC: 1:200-1:400 |
| 别 名 : |
Calcitonin gene-related peptide 1 (Precursor); CGRP-1; Alpha-type CGRP |
|
形 态 : |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 : |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 : |
http://www.abbiotec.com/antibodies/alpha-cgrp-a1-antibody |
| 标 记 物 : |
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产品说明 : |
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