| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse OAT-1. |
|
产品描述 ： |
The organic anion transporter 1 (OAT-1 or SLC22A6) is localized to the basolateral membrane of renal tubular epithelial cells and plays a critical role in the excretion and detoxification of anionic compounds. OAT-1 functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). OAT-1 mediates the sodium-independant uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV) and many other organic compounds. |
| 适用物种 ： |
M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别 名 ： |
Solute carrier family 22 member 6; Organic anion transporter 1; OAT1; Renal organic anion transporter 1; ROAT1; Novel kidney transcript; NKT; SLC22A6 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and immunogen affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Naud J et al. 2011. Drug Metabolism and Disposition. 39(8):1363-1369. PMID# 21525170. [2] Eisner C et al. 2010. Kidney International. 77:519-526. PMID# 20032962. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/oat-1-mouse-antibody |
| 标 记 物 ： |
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产品说明 ： |
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