| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse P-glycoprotein 3. |
|
产品描述 ： |
P-glycoprotein 1 (multidrug resistance protein 1, MDR1) is an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Genetic variation in MDR1 are the cause for patients who do not respond to drug treatment. In mouse, the MDR gene family includes three or more related but distinct cellular genes. MDR1A is also called P-glycoprotein 3. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
Cat. 250820 recognizes human P-glycoprotein 1 (MDR1) and mouse P-glycoprotein 3 (MDR1A). E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别 名 ： |
Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD243; ABCB1; MDR1; PGY1; Multidrug resistance protein 1A; ATP-binding cassette sub-family B member 1A; P-glycoprotein 3; ABCB1a; MDR1A; PGY3; Multidrug resistance protein 3; Abcb4; Mdr3; Pgy-3 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
McCaffrey G et al. 2012. Pre-clinical Systematic Reviews. 122(5):200-213. PMID# 22716933 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/p-glycoprotein-antibody |
| 标 记 物 ： |
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产品说明 ： |
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