| 克隆类型 ： |
Mouse Polyclonal Antibody |
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亚 型 ： |
Mouse Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PP-1. |
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产品描述 ： |
The protein phosphatase 1 (PP1) is essential for cell division and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PP-1 is involved in the regulation of ionic conductances and long-term synaptic plasticity. PP-1 plays an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. PP-1 holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The PP1 catalytic subunit can be PP1-alpha (PPP1CA), PP1-beta (PPP1CB) or PP1-gamma (PPP1CC), which is folded into its native form by inhibitor 2 and glycogen synthethase kinase 3, and then complexed to one or several targeting or regulatory subunits. This antibody recognizes PP1-alpha, PP1-beta and PP1-gamma. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
Product Cat. No. 250829 recognizes PP1-alpha, PP1-beta and PP1-gamma. E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500 |
| 别 名 ： |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A; PPP1CA; PPP1A; Serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CB; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP-1G; Protein phosphatase 1C catalytic subunit; PPP1CC |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/pp-1-antibody |
| 标 记 物 ： |
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产品说明 ： |
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