| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PSD-95. |
|
产品描述 ： |
PSD-95 is a molecular scaffolding protein that binds and clusters NMDA receptors at neuronal synapses. PSD-95 is involved in the guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. PSD-95 heteromultimerizes with DLG2 and together they are recruited into the same NMDA receptor and potassium channel clusters. They may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别 名 ： |
PSD-95; Disks large homolog 4; Postsynaptic density protein 95; Synapse-associated protein 90; SAP90; DLG4; PSD95 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Wessel L et al. 2013. Cell Mol Life Sci. doi: 10.1007/s00018-013-1448-4. PMID# 23982753. [2] Cheng CF et al. 2015. Pain. 156(11): 2295-309. PMID# 26121254. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/psd-95-antibody |
| 标 记 物 ： |
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产品说明 ： |
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