| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SMMHC. |
|
产品描述 ： |
Smooth muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC), and 2 regulatory light chain subunits (MLC-2). Smooth muscle myosin heavy chain (myosin-11 or SMMHC), a cytoplasmic structural protein, is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development and specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. Defects in SMMHC are the cause of aortic aneurysm familial thoracic type 4 and a chromosomal aberration involving SMMHC is found in acute myeloid leukemia. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别 名 ： |
Myosin-11; Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC; MYH11 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Staus D et al. 2011. Arterioscler Thromb Vasc Biol. 31:360-367. PMID# 21106951. [2] Zaman A et al. 2011. Experimental Biology Medicine. 236(5):598-603. PMID# 21521712. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/smmhc-antibody |
| 标 记 物 ： |
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产品说明 ： |
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