| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
mouse IgG3 |
|
产品描述 ： |
The CD20 (HI47) antibody recognizes a 33-37 kDa type-III non-glycosylated phosphoprotein spanning the cell membrane four times therefore called TM4. CD20 antigen is expressed on pre-B cells, resting/activated B cells and corresponding neoplastic B cells, but is absent from plasma cells. CD20 regulates B lymphocyte activation and proliferation. The antibody also reacts with several dendritic, endothelial, epithelial, activated T cells and macrophages. The antibody stains 8-16% of normal peripheral blood lymphocytes. The CD20 (HI47) Antibody inhibits B lymphocyte activation and proliferation. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, FC, IHC, B |
| 应用说明 ： |
Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500 |
| 别 名 ： |
B-lymphocyte antigen CD20; Membrane-spanning 4-domains subfamily A member 1; B-lymphocyte surface antigen B1; Leu-16; Bp35; MS4A1; CD20 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Gupta P. et al 2010. Blood. 116(17):3258-67. doi: 10.1182. PMID#20628151. Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 huma |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd20-hi47-antibody |
| 标 记 物 ： |
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产品说明 ： |
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