| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1 |
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产品描述 ： |
The CD71 (HI166) Antibody recognizes a 95-kDa disulfide-bonded homodimeric type-II transmembrane glycoprotein called transferring receptor (TfR). CD71 antigen is expressed typically at high level on all proliferating cell, activated cells and erythroblasts or reticulocytes that require iron, but not on resting peripheral blood leucocytes and mature erythrocytes. CD71 antigen is also expressed at high level on cells of most neoplastic cell lines and 29-32% of bone marrow cells. A soluble form of CD71 in serum (plasma) exists besides a membrane form. Monitoring the soluble form of CD71 antigen in plasma is a diagnostic marker of anemia besides assaying plasma ferritin. The CD71 (HI160) antibody inhibits CD71/Transferrin receptor activity. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, FC, IHC, B |
| 应用说明 ： |
Purified antibody is suitable for blocking transferrin receptor activity and for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500 |
| 别 名 ： |
Transferrin receptor protein 1; TfR1; TR; TfR; Trfr; T9; p90; CD71 antigen; TFRC |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
Yang CY., et al. 1990. ACTA Academiae Medicinae Sinicae. 12(6): 400; Yang CY., et al. 1992. Chinese J. Microbiology and Immunology. 12(3): 178; Yang CY., et al. 1993. Tissue Antigens. 42(4): 253; Schl |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd71-hi166-antibody |
| 标 记 物 ： |
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产品说明 ： |
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