| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
mouse IgG2a |
|
产品描述 ： |
The CD235a (HI264) antibody recognizes glycophorin-A (GPA), a single-pass membrane sialoglycoprotein. CD235a is the carrier of blood group M and N specificities, which provide the cells with a large mucin-like surface acting as a barrier to cell fusion by minimizing aggregation between red blood cells in the circulation. CD235a is also a membrane inhibitor of reactive lysis. CD235a is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells. Mature erythrocytes are CD235a positive but CD45 and CD71 negative. CD235a is a receptor for influenza virus, Plasmodium falciparum EBA-175 and hepatitis A virus. The CD235a (HI197) antibody recognizes papain-sensitive epitopes located in the extracellular specific domain of CD235a, and therefore agglutinating papain-treated cells. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, FC |
| 应用说明 ： |
E: 1:500-1:1,000; FC: 1:200-1:1,000 |
| 别 名 ： |
CD235a; Glycophorin-A; PAS-2; Sialoglycoprotein alpha; MN sialoglycoprotein; GYPA; GPA |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
David M., et al. 2002. Leucocyte Typing VII: White Cell Differentiation Antigens. P577-582. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd235a-hi264-antibody |
| 标 记 物 ： |
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产品说明 ： |
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