| 克隆类型 ： |
Mouse Monoclonal Antibody, FITC-conjugated Antibody |
|
亚 型 ： |
mouse IgG1 |
|
产品描述 ： |
The CD22 (HIB22) antibody recognizes a 130-140 kDa type-I transmembrane glycoprotein that is a B cell restricted antigen. CD22 antigen is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B lymphocytes. CD22 expression is increased after activation and lost at the terminal stage of B cell differentiation. Most B cell leukemias and lymphomas also express CD22. It is not expressed in T cells, monocytes and granulocytes. CD22 is an early marker for B-ALL and hairy-cell leukemia diagnostic. CD22 is an adhesion molecule that amplifies the signal of B cell activation. CD22 ligands are CD45RO antigen on T cells and CD75 antigen on B cells participating in the homotopic interaction of T and B cells. |
| 适用物种 ： |
H |
|
应用范围 ： |
FC |
| 应用说明 ： |
FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000 |
| 别 名 ： |
B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; Leu-14; B-lymphocyte cell adhesion molecule; BL-CAM; CD22; SIGLEC2 |
|
形 态 ： |
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
|
产品文献 ： |
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd22-hib22-antibody-0 |
| 标 记 物 ： |
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产品说明 ： |
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