| 克隆类型 ： |
Rabbit Polyclonal Antibody, Modification Specific Antibody, Biotin-conjugated Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
Acetylated KLH-conjugates |
|
产品描述 ： |
DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds DNA by acetylation of lysine residues of histones. Research has shown that acetylation of non-histone proteins (e.g. transcription factors) and histones are involved in transcription. Histone acetyltransferases (HAT) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) on lysine residues, whereas histone deacetylases (HDAC) remove them. This pan-specific antibody recognizes proteins with acetyllysine residues. This antibody has been utilized for proteomic studies of protein acetylation, immunoaffinity chromatography separation and isolation of acetylated proteins and peptides from protease-digested whole cells.
|
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IP, IHC |
| 应用说明 ： |
Cat. No. 251116 has been tested on acetylated histones, acetylated BSA and acetylated MBP. There is no reaction with non-acetylated proteins. E: 1:500-1:2,000; WB: 1:200-1:1000; IHC: 1:100-1:500 |
| 别 名 ： |
Acetylated Lysine; AcK; Acetyllysine; Acetyl-lysine; AcLys |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.4 ml (0.25 mg/ml) of PBS pH7.4, 50% glycerol. Antibody was purified by using acetyllysine-affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/acetylated-lysine-antibody-1 |
| 标 记 物 ： |
|
|
产品说明 ： |
|
|
