| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human COX-1. |
|
产品描述 ： |
Cyclooxygenase-1 (COX-1) is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. Classical non-steroidal anti-inflammatory drugs (NSAIDS) inhibit COX-1 and COX-2, which reduces inflammation and induces an an analgesic effect. The non-slelective pharmacological inhibition of COX-1 has been shown to be a main cause of the gastrointestinal (GI) tract irritation associated with classical NSAIDS as the prostaglandins produced by COX-1 are involved in the maintenance of gastric mucosa. Newer generation anti-inflammatory drugs which selectively inhibit COX-2 have been shown to have minimal GI tract irritation. |
| 适用物种 ： |
H, M, R, Ck |
|
应用范围 ： |
E, WB, IHC, IP |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 别 名 ： |
COX-1; Prostaglandin-endoperoxide synthase-1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; PTGS1; COX1 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cox-1-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
|
