| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD183. |
|
产品描述 ： |
C-X-C chemokine receptor type 3 (CXCR-3, CD183) is a receptor for CXCL9, CXCL10 and CXCL11 that mediates the proliferation of human mesangial cells (HMC). CD183 isoform 2 is a receptor for CXCL4 that mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). Isoform 3 mediates the activity of CXCL11. Isoforms 1 and 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别 名 ： |
CXC-R3; CD183; C-X-C chemokine receptor type 3; CXCR-3; Interferon-inducible protein 10 receptor; IP-10 receptor; CKR-L2; G protein-coupled receptor 9; GPR9; CXCR3 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Tsutahara k et al. 2012. Nephrol. Dial. Trandsplant. (2012) 27 (10):3799-3806. PMID# 22904101. [2] Milicevic N et al. 2011. Medicine. Histochemistry And Cell Biology. 135(6): 593-601. PMID# 2161 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd183-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
