| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD14. |
|
产品描述 ： |
Monocyte differentiation antigen CD14 (CD14) cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. CD14 up-regulates cell surface molecules, including adhesion molecules. CD14 is expressed strongly on the surface of monocytes and weakly on the surface of granulocytes. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别 名 ： |
Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14; Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Singla D et al. 2015. PLoSONE. 10(3): e0120739. PMID 25768089. [2] Ayman A et al. 2014. Am J Reprod Immunol. 71(3): 241-251. PMID# 24372928. [3] Allam AB. et al. 2013. Am J Reprod Immunol. PMID 2 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd14-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
