Pan-Cadherin Antibody

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产品名称 ： Pan-Cadherin Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 251786

规　　格 ： 0.1mg

详细信息

克隆类型：	Mouse Monoclonal Antibody
亚　　型：	Mouse IgG1
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of chicken pan-cadherin.
产品描述：	Cadherins are calcium dependent cell adhesion proteins. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells. Cadherins contribute to the sorting of heterogeneous cell types. N-cadherin functions during gastrulation and is required for establishment of left-right asymmetry. N-Cadherin is commonly found in cancer cells and provides a mechanism for transendothelial migration. When a cancer cell adheres to the endothelial cells of a blood vessel it up-regulates the src kinase pathway which phosphorylates beta-catenins attached to both N-cadherin and E-cadherins.
适用物种：	H, M, R, Rb, Ck
应用范围：	E, WB, IHC
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
别　　名：	Pan-Cadherin; Cadherin; CDH; Cadherin-2; DH2; Neural cadherin; N-cadherin
形　　态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
产品文献：	Pranjal Sarma et al. 2015. Centre for Chemical Biology; CSIR-Indian Institute of Chemical Technology. Oct. 16(10): 1486–1501. PMID: 26192233.
产品链接：	http://www.abbiotec.com/antibodies/pan-cadherin-antibody
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产品说明：

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