| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within human ADAM-TS2 protein. |
|
产品描述 ： |
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS2) cleaves the propeptides of type I and II collagen prior to fibril assembly. ADAM-TS2 does not act on type III collagen. ADAM-TS2 also plays a role in development that is independent of its role in collagen biosynthesis. ADAM-TS2 cleaves the N-propeptide of collagen chain alpha-1(I) at Pro-|-Gln and of alpha-1(II) and alpha-2(I) at Ala-|-Gln. It is expressed at high level in skin, bone, tendon and aorta and at low levels in thymus and brain. Defects in ADAMTS2 are the cause of Ehlers-Danlos syndrome type 7C (EDS7C). EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:1,000-1:10,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别 名 ： |
A distintegrin and metalloproteinase with thrombospondin motifs 2; ADAMTS-2; ADAM-TS 2; ADAM-TS2; Procollagen I/II amino propeptide-processing enzyme; Procollagen I N-proteinase; PC I-NP; Procollagen N-endopeptidase; pNPI; ADAMTS2; PCINP; PCPNI |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5 % BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/adam-ts2-antibody |
| 标 记 物 ： |
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产品说明 ： |
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