APE1 Antibody_华拓生物

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APE1 Antibody

产品名称 ： APE1 Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 252079

规　　格 ： 0.1mg

详细信息

克隆类型：	Rabbit Polyclonal Antibody
亚　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human APE1.
产品描述：	DNA-(apurinic or apyrimidinic site) lyase (APE1) is a multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APE1 are DNA repair and redox regulation of transcriptional factors. APE1 functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. APE initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
适用物种：	H
应用范围：	E, WB
应用说明：	E: 1:10,000-1:50,000; WB: 1:100-1:1,000
别　　名：	DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1; APE; APE1; APEX; APX; HAP1; REF1; APEX1
形　　态：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
产品链接：	http://www.abbiotec.com/antibodies/ape1-antibody
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