| 克隆类型 ： |
Rabbit Polyclonal Antibody, Phosphospecific Antibody |
|
亚 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr202/Tyr204 of rat ERK/MAPK. |
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产品描述 ： |
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK/MAPK is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. The activity of ERK/MAPK is regulated by dual phosphorylation at Thr202 and Tyr204. |
| 适用物种 ： |
B, D, Ck, M, X, Zf |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:1,000; WB: 1:1,000; IHC: 1:500 |
| 别 名 ： |
ERK-1; Mitogen-activated protein kinase 3; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAPK1; p44-ERK1; ERT2; p44-MAPK; Microtubule-associated protein 2 kinase; MAPK3; ERK1; PRKM3; and for ERK-2; Mitogen-activated protein kinase 1; Extracellular signal-regulated kinase 2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK2; p42-MAPK; ERT1; MAPK1; ERK2; PRKM1; PRKM2 |
|
形 态 ： |
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/erkmapk-thr202tyr204-antibody |
| 标 记 物 ： |
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产品说明 ： |
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