PAK-1/2/3 (Thr402) Antibody

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产品名称 ： PAK-1/2/3 (Thr402) Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 252569

规　　格 ： 0.1ml

详细信息

克隆类型：	Rabbit Polyclonal Antibody, Phosphospecific Antibody
亚　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr402 of rat PAK-1, 2, 3. Thr402 in PAK-2 corresponds to Thr423 in human PAK-1.
产品描述：	Serine/threonine-protein kinase PAK-1 (PAK-1) is a protein kinase that acts on a variety of targets. PAK-1 is the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. PAK-1 is activated by CDC42 and RAC1, and is involved in dissolution of stress fibers and reorganization of focal complexes. PAK-1 is involved in regulation of microtubule biogenesis through phosphorylation of TBCB. PAK-1 activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. Autophosphorylation of Thr402 has been found to be essential for activation of PAK.
适用物种：	B, D, H, M, R
应用范围：	E, WB
应用说明：	E: 1:1,000; WB: 1:1,000
别　　名：	Serine/threonine-protein kinase PAK 1; p21-activated kinase 1; PAK-1; p65-PAK; Alpha-PAK; PAK1
形　　态：	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
产品链接：	http://www.abbiotec.com/antibodies/pak-123-thr402-antibody
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