| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human BCL-10 expressed in E. coli. |
|
产品描述 ： |
Bcl-10 (B-cell CLL/lymphoma 10) is a protein containing a caspase recruitment domain (CARD). It plays an important
role in apoptosis and activating NF-kappa. Bcl-10 interacts with CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
|
| 适用物种 ： |
H, M |
|
应用范围 ： |
E, WB, IHC, IF, FC |
| 应用说明 ： |
E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000; FC: 1:200-1:400 |
| 别 名 ： |
Bcl-10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; CARD-containing molecule enhancing NF-kappa-B; Cellular homolog of vCARMEN; cCARMEN; Mammalian CARD-containing adapter molecule E10; mE10; Cellular-E10; c-E10; CARD-like apoptotic protein; hCLAP; BCL10; CIPER; CLAP |
|
形 态 ： |
Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/bcl-10-4f8-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
