| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human CD31 expressed in E. coli. |
|
产品描述 ： |
CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31 has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily. |
| 适用物种 ： |
H |
|
应用范围 ： |
WB, IHC, IF |
| 应用说明 ： |
E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000 |
| 别 名 ： |
CD31; Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1 |
|
形 态 ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd31-2f7b-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
|
