| 克隆类型 ： |
Mouse Monoclonal Antibody |
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亚 型 ： |
Mouse IgG1 |
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免 疫 原 ： |
Purified recombinant fragment of SORL1(aa2159-2214) expressed in E. coli. |
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产品描述 ： |
SORL1 (Sortilin-related receptor, LA repeats containing) is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytosis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
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| 适用物种 ： |
H |
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应用范围 ： |
WB |
| 应用说明 ： |
WB: 1:500-1:2000;
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| 别 名 ： |
Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repeats; SorLA; SORL1; C11orf32 |
|
形 态 ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/sorl1-7d7b-antibody |
| 标 记 物 ： |
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产品说明 ： |
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