PTEN (1B8) Antibody_华拓生物

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PTEN (1B8) Antibody

产品名称 ： PTEN (1B8) Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 252929

规　　格 ： 0.1ml

详细信息

克隆类型：	Mouse Monoclonal Antibody
亚　　型：	Mouse IgG1
免疫原：	Purified recombinant fragment of PTEN expressed in E. coli.
产品描述：	PTEN (Phosphatase and tensin homolog) is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins. PTEN has also a lipid phosphatase activity that is critical for its tumor suppression function. PTEN antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. Defects in PTEN are the cause of numerous cancers such as in Cowden disease (breast, thyroid and skin cancer predisposition), Lhermitte-Duclos disease, and head and neck squamous cell carcinoma.
适用物种：	H, M
应用范围：	E, WB, FC, IF
应用说明：	E: 1-10000; WB: 1:500-1:2000; IF: 1:200-1:1000; FC: 1:200-1:400
别　　名：	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Phosphatase and tensin homolog; Mutated in multiple advanced cancers 1; MMAC1, TEP1
形　　态：	Each vial contains 0.1 ml IgG in PBS pH7.4, 50% glycerol with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存条件：	Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
产品链接：	http://www.abbiotec.com/antibodies/pten-1b8-antibody
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