| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG2b |
|
免 疫 原 ： |
Purified recombinant fragment of human MAPK1 expressed in E. coli. |
|
产品描述 ： |
ERK1 and ERK2 (Extracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK1 and ERK2 are involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. |
| 适用物种 ： |
H, M |
|
应用范围 ： |
WB, FC |
| 应用说明 ： |
WB: 1:500-1:2000;
FC: 1:200-1:400;
|
| 别 名 ： |
ERK-1; Mitogen-activated protein kinase 3; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAPK1; p44-ERK1; ERT2; p44-MAPK; Microtubule-associated protein 2 kinase; MAPK3; ERK1; PRKM3; and for ERK-2; Mitogen-activated protein kinase 1; Extracellular signal-regulated kinase 2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK2; p42-MAPK; ERT1; MAPK1; ERK2; PRKM1; PRKM2 |
|
形 态 ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/erk12-3f8-antibody |
| 标 记 物 ： |
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产品说明 ： |
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