KLHL13 (8D1) Antibody

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产品名称 ： KLHL13 (8D1) Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 253027

规　　格 ： 0.1ml

详细信息

克隆类型：	Mouse Monoclonal Antibody
亚　　型：	Mouse IgG1
免疫原：	Purified recombinant fragment of human KLHL13 expressed in E. coli.
产品描述：	KLHL13 (Kelch-like protein 13) is a 604 amino acid long protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.
适用物种：	H
应用范围：	E, WB, IHC, IF, FC
应用说明：	E: 1:10000; WB: 1:500-1:2000; IF: 1:200-1:1000; IHC: 1:200-1:1000; FC: 1:200-1:400
别　　名：	Kelch-like protein 13; BTB and kelch domain-containing protein 2; BKLHD2; KIAA1309; KLHL13
形　　态：	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
保存条件：	Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
产品链接：	http://www.abbiotec.com/antibodies/klhl13-8d1-antibody
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