| 克隆类型 ： |
Rabbit Polyclonal Antibody |
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亚 型 ： |
Rabbit Ig |
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免 疫 原 ： |
Bacterial fusion protein encompassing a 188-aa fragment from the C-term region of mouse periostin. |
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产品描述 ： |
Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Periostin has since been demonstrated to be important in heart valve development and myocardial infarction because it promotes collagen fibrogenesis, inhibits differentiation of progenitor cells into cardiomyocytes and is essential in maintaining the biomechanical properties of the adult myocardium. This antibody detects a 93-kDa periostin doublet, which corresponds to the two largest forms of the alternatively spliced region of periostin with a distinctive staining pattern in IHC. |
| 适用物种 ： |
Ck, H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
Cat. No. 253201 works well in IHC on paraformaldehyde-fixed sections with a citrate-based antigen retrieval protocol. E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:100 |
| 别 名 ： |
Periostin; PN; Osteoblast-specific factor 2; OSF-2; Postn; Osf2 |
|
形 态 ： |
Each vial contains 0.1 ml IgG in PBS pH7.4 with 0.065% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/periostin-c-term-antibody |
| 标 记 物 ： |
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产品说明 ： |
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