NOD3 Antibody_华拓生物

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NOD3 Antibody

产品名称 ： NOD3 Antibody

中文名称 ：

产品类别 ：一抗

品　　牌 ： ABBIOTEC

货　　号 ： 254340

规　　格 ： 0.1mg

详细信息

克隆类型：	Rabbit Polyclonal Antibody
亚　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within human NOD3.
产品描述：	NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-κB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
适用物种：	H, M, R
应用范围：	E, WB
应用说明：	E: 1:500-1:1,000; WB: 1:100-1:500
别　　名：	NOD3; Nucleotide-binding oligomerization domain containing 3; NLRC3; CLR16.2
形　　态：	Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
保存条件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
产品链接：	http://www.abbiotec.com/antibodies/nod3-antibody
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产品说明：

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