克隆类型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from human CKMT2. |
纯化方式 : |
Immunogen affinity purified |
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
产品描述 : |
CKMT2 (creatine kinase, mitochondrial 2 (sarcomeric)) is a creatine kinase isoenzyme, (reversibly) catalyzing the production of ATP from ADP by converting Phosphocreatine to creatine. Phosphocreatine serves as an energy reservoir for the rapid generation of ATP.Mitochondrial creatine kinase exists as two isoenzymes, sarcomeric mitochondrial creatine kinase (CKMT2) and ubiquitous creatine kinase; these are encoded by separate genes. Mitochondrial creatine kinases occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. The CKMT2 gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. |
适用物种 : |
Hu, Mo, Rat, Dog, Pig, Cow, Hor |
应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
别 名 : |
CKMT 2; Basic-type mitochondrial creatine kinase; CKMT 2; CKMT2; CPK; Creatine kinase mitochondrial 2; Creatine kinase mitochondrial 2 (sarcomeric); Creatine kinase S-type; creatine kinase S-type, mitochondrial; Creatine kinase, sarcomeric mitochondrial; KCRS_HUMAN; Mib CK; Mib-CK; mitochondrial; OTTHUMP00000147542; S-MtCK; Sarcomeric mitochondrial creatine kinase; SMTCK. |
保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
产品说明 : |
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