| 克隆类型 ： |
Rat Monoclonal Antibody；Clone number：53.6.7 |
|
亚 型 ： |
Rat IgG2a |
|
纯化方式 ： |
Concentration：0.5 mg/ml |
|
缓 冲 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
产品描述 ： |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
| 适用物种 ： |
Mouse |
|
应用范围 ： |
FC |
| 应用说明 ： |
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl |
| 保存条件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 标 记 物 ： |
BIOT |
|
产品说明 ： |
|
|
