FOXP3(MF-23)Antiboy;PE Conjugated;流式抗体

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产品名称 ： FOXP3(MF-23)Antiboy;PE Conjugated;流式抗体

中文名称 ：

产品类别 ：流式抗体

品　　牌 ： OTWO(华拓)

货　　号 ： HT1610449

规　　格 ： 25/100 μg

详细信息

克隆类型：	Rat Monoclonal Antibody；Clone number：MF-23
亚　　型：	Rat IgG2b
纯化方式：	Concentration：0.2 mg/ml
缓冲液：	PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述：	FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one (FOXP3) corresponding to the canonical full-length sequence; the other (FOXP3 δ2) lacking exon 2. The 150D monoclonal antibody reacts with human, mouse and rat FOXP3. The 150D antibody recognizes FOXP3 epitope encoded by exon 2.
适用物种：	Mouse
应用范围：	FC
应用说明：	The amount of the reagent is suggested to be used ≤ 1.0 µg /10^6 cells in 100 µl
保存条件：	Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标记物：	PE
产品说明：

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