| 克隆类型 ： |
Monoclonal |
|
亚 型 ： |
IgG1 |
|
免 疫 原 ： |
Full length human recombinant protein of human DCXR in HEK293T cell |
|
纯化方式 ： |
Immunogen affinity purified |
|
缓 冲 液 ： |
PBS, pH 7.3(1% BSA, 50% glycerol, 0.02% sodium azide) |
|
产品描述 ： |
DCXR is a 244 amino acid member of the short-chain dehydrogenases/reductases family. This peripheral membrane protein catalyzes NADPH-dependent reduction of mulitple sugars, including L-xylulose, to the osmolyte xylitol. Producing xylitol in the renal tubules can prevent osmotic stress. L-xylulose reductase functions as a homotetramer and is expressed highly in kidney, liver and epididymis. Essential pentosuria is the result of a partial deficiency of L-xylulose reductase. Red blood cells of normal individuals contain two L-xylulose reductases: a major and a minor isozyme. Red cells from patients with pentosuria contain only one isozyme. |
| 适用物种 ： |
Hu |
|
应用范围 ： |
WB, IHC, ICC/IF |
| 应用说明 ： |
WB: 1:2000 IHC: 1:50 ICC/IF: 1:100 |
| 别 名 ： |
DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR |
| 保存条件 ： |
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted. |
| 标 记 物 ： |
|
|
产品说明 ： |
|
