| 克隆类型 ： |
Rabbit Polyclonal IgG |
|
亚 型 ： |
IgG |
|
免 疫 原 ： |
peptide derived from human PKC eta/PRKCL |
|
纯化方式 ： |
Immunogen affinity purified |
|
缓 冲 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 ： |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). |
| 适用物种 ： |
Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor |
|
应用范围 ： |
E, IHC, IF |
| 应用说明 ： |
E: 1:5000-1:10000 IHC: 1:100-1:500 IF: 1:100-1:500 |
| 别 名 ： |
KPCL_HUMAN; MGC26269; MGC5363; nPKC eta; PKCh; PKCL; PRKCH; PRKCL; Protein kinase C eta; Protein kinase C eta type. |
| 保存条件 ： |
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted. |
| 标 记 物 ： |
|
|
产品说明 ： |
|
