| 克隆类型 ： |
Rabbit Polyclonal IgG |
|
亚 型 ： |
IgG |
|
免 疫 原 ： |
Proenkephalin-A fusion protein |
|
纯化方式 ： |
Immunogen affinity purified |
|
缓 冲 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 ： |
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. |
| 适用物种 ： |
Hu, Mo, Rat |
|
应用范围 ： |
WB，IHC，E |
| 应用说明 ： |
WB: 1:1000-1:5000 E: 1:500-1:2000 IHC: 1:50-1:500 |
| 别 名 ： |
EP-ENK; nkephalin A; PENK; P ENK; Preproencephalin A; Proenkephalin A; Proenkephalin; Synenkephalin; Opioid growth factor; OGF; Leu enkephalin; Met enkephalin; PENK protein; ProenkephalinA; lipotropin gamma |
| 保存条件 ： |
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted. |
| 标 记 物 ： |
|
|
产品说明 ： |
|
|
