|
序 列 ： |
The synthetic peptide used to raise the antibody Cat. No. 200160 is selected from a sequence within the N-term region of human BRCA1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分 子 式 ： |
C88H149N29O31S1 |
|
分 子 量 ： |
2141.3 g/mol |
|
纯 度 ： |
Purity > 80% by HPLC |
|
形 态 ： |
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking e |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存条件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| 产品链接 ： |
http://www.ABBIOTEC.com/peptides/brca1-peptide |
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产品说明 ： |
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| 产品描述 ： |
Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers. |
