产品货号Reference:               CAN-B-4300
检测方法Kit Type:                 Competitive ELISA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 0.1 mg/L
检测样本Sample Type:         Human serum / 20 μL
检测范围Calibrator Range:  0.2–10 mg/L
检测时间Total Assay Time:  80 minutes

背景介绍：

β2-微球蛋白是一条由10 0个氨基酸组成的单肽链，存在于有核细胞表面。β-2-M被持续分泌到循环系统中，从而维持一个平衡的血清水平。
诊断意义：
肾小球滤过率的降低导致β2-微球蛋白水平的升高。
β2-微球蛋白是诊断肾脏疾病和活动期类风湿关节炎的有用指标。
获得性免疫缺陷综合征(Acquired Immune deficiency syndrome，AIDS)患者血清β-2-M水平升高。
检测的血清样本总数为92份，在男性、绝经前和绝经后女性的正常水平之间差异不大。男性样本的平均值为1.582 mg/L，绝经前女性的平均值为1.457 mg/L，绝经后女性的平均值为1.608 mg/L，青年人的平均值为1.13 mg/L。
β2-Microglobulin (β2-M) is a single polypeptide chain containing 100 amino acids and is found on the surface of nucleated cells. β2-M is continuously secreted into the circulatory system and therefore maintains a balanced serum level.
Clinical Trends:
Decreases in the glomerular filtration rate gives rise to increases in the level of β2-M.
β2-M is a helpful marker in the diagnosis of kidney disease and active rheumatoid arthritis.
Patients with acquired immune deficiency syndrome (AIDS) show an increased level of β2-M.
β2-M has a low concentration in serum. We have found in a normal unselected population that in serum the highest level for β2-M is 3.8 mg/L. The total number of serum samples tested was 92, showing little differences in the normal level in males, pre- and postmenopausal females. The average for male samples = 1.582 mg/L, for premenopausal female = 1.457 mg/L, for postmenopausal female = 1.608 mg/L and finally for young people = 1.13 mg/L.