产品货号Reference:              CAN-ALD-500
检测方法Kit Type:                 Competitive ELISA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 9.1 pg/mL
检测样本Sample Type:         Human serum, plasma, or urine / 50 μL
检测范围Calibrator Range:  15–1000 pg/mL
检测时间Total Assay Time:  80 minutes

背景介绍：

醛固酮是一种强有力的矿物质醛固酮，它的合成和释放受体内肾素-血管紧张素系统的控制。醛固酮促进肾脏远端小管对钠的重吸收，导致钾的分泌和钠的滞留，从而控制循环血容量。醛固酮的长期过度生产和分泌导致高血压。测定血清醛固酮水平和血浆肾素活性水平可用于鉴别原发性醛固酮增多症和继发性醛固酮增多症。
Aldosterone is a potent mineralocorticoid whose synthesis and release are controlled by the renin-angiotensin system of the body. Aldosterone promotes the reabsorption of sodium in the distal tubules of the kidney resulting in potassium secretion along with sodium retention, which controls the circulating blood volume. Chronic overproduction and secretion of aldosterone leads to hypertension.
Measurement of aldosterone levels in serum in conjunction with plasma renin activity levels can be used to differentiate between primary and secondary aldosteronism.