产品说明 :
产品货号Reference:CAN-E-440
检测方法Kit Type:Competitive ELISA
规格Kit Size:96-well break-apart microplate
灵敏度Sensitivity:4.4 pg/mL
检测样本Sample Type:Human serum / 25 μL
检测范围Calibrator Range:20–10,000 pg/mL
检测时间Total Assay Time:2 hours 15 minutes
背景介绍:
总雌激素包括雌酮、雌二醇和雌三醇的总量。雌激素参与了女性性器官的发育和第二性征的发生。在卵子受精之前,雌激素的主要作用是影响生殖道的生长和功能,为受精的卵子做准备。在月经周期的卵泡期,总雌激素水平略有升高。总雌激素的产生随后显着增加,在第13天左右达到高峰。峰值持续时间短,到第16天的周期水平将会很低。第二个高峰出现在周期的第21天左右;如果不进行受精,总雌激素的产生就会减少。在绝经后妇女,所有雌激素的浓度显着降低,雌激素成为主要的雌激素。在孕妇中,所有雌激素的浓度上升,雌三醇成为主要的雌激素。
Total estrogens comprise the total quantity of estrone, estradiol, and estriol. The estrogens are involved in the development of female sex organs and secondary sex characteristics. Before the ovum is fertilized the main action of the estrogens is on the growth and function of the reproductive tract to prepare it for the fertilized ovum. During the follicular phase of the menstrual cycle the total estrogens level shows a slight increase. The production of total estrogens then increases markedly to peak at around day 13. The peak is of short duration and by day 16 of the cycle levels will be low. A second peak occurs at around day 21 of the cycle; if fertilization does not occur, the production of total estrogens decreases. In post-menopausal women the concentration of all estrogens decreases substantially and estrone becomes the predominant estrogen. In pregnant women the concentration of all estrogens escalates and estriol becomes the predominant estrogen.