CDX-2是肠上皮细胞表达的一种与尾相关的同源盒转录因子。CDX-2是一种有用的胃肠道肿瘤标记物，可用于确定胃肠道转移性腺癌和类癌的起源。抗CDX-2可用于鉴别肺腺癌和转移性大肠腺癌，而卵巢黏液性癌也可与抗CDX-2呈阳性反应，从而限制了与转移性大肠腺癌的鉴别能力。

CDX-2 is a caudal-related homeobox transcription factor that is expressed by intestinal epithelial cells. CDX-2 is a useful marker for gastrointestinal carcinoma, and for determining the origin of gastrointestinal metastatic adenocarcinoma and carcinoids. Anti-CDX-2 is used for differentiating lung and metastatic colorectal adenocarcinoma, however mucinous ovarian carcinoma also react positively with Anti-CDX-2, thereby limiting the ability to differentiate from metastatic colorectal adenocarcinoma.

 

Clone                    IHC402

Source                  Mouse Monoclonal

Positive Control Colon

Dilution Range 1:50-1:200

 

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