T淋巴细胞膜蛋白3(TIM3)存在于T辅助细胞1型淋巴细胞和其他免疫细胞，包括树突状细胞和自然杀伤细胞。TIM3在CD4+肿瘤浸润淋巴细胞中过表达，包括与预后不良相关的非小细胞肺癌。TIM3最近成为肿瘤免疫治疗的潜在靶点。

T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.

 

Clone: IHC003

Source: Mouse Monoclonal

Positive Control: Tonsil

Dilution Range: 1:100 - 1:400

 

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