深圳市豪地华拓生物科技有限公司

英文名称 ： 5α-Androstane-3α, 17β diol Glucuronide(3α-Diol G) Kit

检测样本 ： Human Serum

产品说明 ：

产品货号Reference:             CAN-DG-460
检测方法Kit Type:                Competitive ELISA
规格Kit Size:                        96-well break-apart microplate
灵敏度Sensitivity:                0.1 ng/mL
检测样本Sample Type:         Human serum / 50 μL
检测范围Calibrator Range:  0.25–50 ng/mL
检测时间Total Assay Time:  45 minutes

 

背景介绍：

 
5-α-雄甾烷-3-α，17-β-二醇葡萄糖醛酸是一种C19类固醇，简称3-α-Diol G，5α-Diol G或简写为α-Diol G，它主要是作为睾酮和双氢睾酮（DHT）的代谢产物而产生的。它主要产生于靶外周组织，如皮肤，尤其是毛囊周围。大量的3-α-DiolG刺激会导致过度的毛发形成，特别是在女性通常毛发应不多的情况下。
近年来研究特发性多毛症妇女的临床研究人员对这种类固醇的测量越来越感兴趣。
5α-Androstane-3α, 17β-diol glucuronide is a C19 steroid and is either abbreviated as 3α-Diol G, 5α-Diol G or simply, α-Diol G. It is produced mainly as a metabolite of testosterone and dihydrotestosterone (DHT). It is largely produced in target peripheral tissues such as the skin, especially around hair follicles. The stimulation by large amounts of 3α-Diol G leads to excessive hair formation, notably where hair is not normally present in women.

In recent years the interest in the measurement of this steroid has increased among clinical investigators studying women suffering from idiopathic hirsutism.